Schlagwort: Enzyme
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Neprilysin
Directed Evolution (DE) in Enzyme Engineering example 2 engineered neprilysin with improved amyloid beta activity and specificity here at first only: „Engineering Neprilysin Activity and Specificity to Create a Novel Therapeutic for Alzheimer’s Disease“ Carl I. Webster, Matthew Burrell, Lise-Lotte Olsson, Susan B. Fowler, Sarah Digby, Alan Sandercock, Arjan Snijder, Jan Tebbe, Ulrich Haupts, Joanna…
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HPPD variants
„4-Hydroxyphenylpyruvate dioxygenase (HPPD, EC 1.13.11.27) is an enzyme engaged in photosynthetic activity and catalyzes the transformation of 4-hydroxyphenylpyruvic acid (HPPA) into homogentisic acid (HGA). HPPD inhibitors constitute a promising area of discovery and development of innovative herbicides with some advantages, including excellent crop selectivity, low application rates, and broad-spectrum weed control. HPPD inhibitors have been…
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# divers eins
The Nobel Prize in Chemistry 2020 was awarded jointly to Emmanuelle Charpentier and Jennifer A. Doudna „for the development of a method for genome editing„ https://www.nobelprize.org/prizes/chemistry/2020/summary/ The Nobel Prize in Chemistry 2018 was divided, one half awarded to Frances H. Arnold „for the directed evolution of enzymes“, the other half jointly to George P. Smith…